Does benzo[a]pyrene affect the heart embryonic development?

Authors

  • Łukasz M. Kołodziejczyk Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland
  • Magdalena Puzik Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland
  • Agnieszka Greń Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland
  • Marta Batoryna Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland
  • Grzegorz Formicki Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland
  • Edyta Kapusta Department of Animal Physiology and Toxicology, Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland

DOI:

https://doi.org/10.24917/25438832.3supp.4

Keywords:

benzo[a]pyrene, ecg, embryo, GSH, heart, MDA

Abstract

Benzo[a]pyrene is a polycyclic aromatic hydrocarbon of well proved toxic effect on animal cells and tissues. We used chicken in ovo developmental model to verify its influence on selected parameters of the heart rhythm and on the antioxidative defense in the heart tissue. We determined that the dose of 1 mg/kg weight of eggs of benzo[a]pyrene strongly activates the glutathione-dependent antioxidative system, but it do not significantly affect the heart conducting system of the chicken embryo. We postulate that further study on the benzo[a]pyrene action during embryonic development of birds is recommended.

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References

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Published

2018-12-31

How to Cite

Kołodziejczyk , Łukasz M., Puzik , M., Greń , A., Batoryna , M., Formicki , G., & Kapusta , E. (2018). Does benzo[a]pyrene affect the heart embryonic development?. Annales Universitatis Paedagogicae Cracoviensis Studia Naturae, 3(2), 33–38. https://doi.org/10.24917/25438832.3supp.4

Issue

Issue No. 3 (supp.)

Section

Artykuły